Research / activities
Research / activities

研究内容

We are conducting research on the control of infectious diseases mainly in Asia.

Teikyo University Asia International Infectious Disease Control aims to control infectious diseases in the Asian region by promoting research on respiratory infections, mainly respiratory infections, elucidation of their testing methods, elucidation of the pathogenic mechanism, and development of treatment methods.

1. Research on infectious diseases

  • Analysis of mutations in the new coronavirus (SARS-Cov-2)
  • Analysis of pathogenic microorganisms such as influenza virus and Acinetobacter
  • Infectious diseases in Asia: Elucidation of the pathogenic mechanism and development of treatment methods for respiratory infections caused by influenza (AH5N1) virus, etc.

2. Research on infectious disease control factors

  • Functional analysis of neutrophils, macrophages, and dendritic cells
  • Analysis of inflammatory factors such as antiviral cytokines and inflammatory cytokines
  • Analysis of heme-type peroxidase (Myeroperoxidase and Lactoperoxidase) functions
  • Analysis of inflammation induction mechanism by enzymatic reaction products of heme-type peroxidase (hypochlorous acid and hypothiocyanate)

3. Research on infectious disease-induced inflammatory diseases

The development of intractable inflammatory diseases such as vasculitis can also be triggered by infections. At this institute, we are conducting research by analyzing the relationship between infectious diseases and the onset of vasculitis, focusing on the types of inflammatory cytokines and inflammatory cells that cause inflammation.

4. Studies related to "severe pneumonia" caused by viral infections

The transmission of respiratory tract infections caused by influenza virus and the like is a global threat, and we are conducting research on the selection of candidates for therapeutic agents for severe influenza pneumonia. Among them, we are also researching and reporting on the antiviral activity of existing macrolide antibiotics such as leucomycin A3 (josamycin) and azithromycin.

Candidates for treatment of severe influenza pneumonia: leucomycin A3 (josamycin)
Sugamata R, et al. Leucomycin A3 (LM-A3), a 16membered macrolide antibiotic, inhibits Influenza A virus infection and disease progression. J Antibiot (Tokyo). 2014 Mar; 67 (3): 213-22. Doi: 10.1038 / ja.2013.132. Epub 2014 Feb 5.

Azithromycin showing potential as a candidate for viral treatment
Tran DH, et al. Azithromycin, a 15-membered macrolide 1 antibiotic, inhibits influenza A (H1N1) pdm09 virus infection by interfering with virus internalization process. J Antibiot (Tokyo). 2019; 72: 759-768. Doi: 10.1038 / s41429-019-0204-x. Epub 2019 Jul 12.

5. International joint research and international exchange

International joint research

Invitation of foreign research students
We are aiming for further development of international joint research by accepting foreign students from the Asian region as Graduate School students and promoting research.

Japan Agency for Medical Research and Development (AMED)
Through the e-ASIA JRP program, we are participating in a joint international research project based on international cooperation among the three countries of Japan, Vietnam, and the Philippines.

International Exchange

[The Sakura Science Plan (SSP) of the Japan Science Promotion Organization invites doctors, nurses, and pharmacists from Asian countries as short-term study abroad programs to exchange technical opinions and exchange internationally.
We also provide on-the-job training on public health, infectious disease control, and infectious disease treatment at medical facilities in the Asian region for students, Graduate School students, and residents who belong to Teikyo University.

研究論文

Has published many research papers

This institute publishes research results in various forms in English and Japanese, and contributes to the further progress of research.

ADC member dissertation list

International Exchange

The Asia International Institute of Infectious Diseases Control, Teikyo University has made numerous achievements in the field of infectious disease research in the Asian region, and has been aiming to improve research and technology at participating facilities in Vietnam (partly Laos) and the Philippines since 2014. , Promoting infectious diseases related to respiratory diseases. Currently, we are accepting government-sponsored international students (Graduate School of Medicine) from the Ministry of Education, Culture, Sports, Science and Technology to elucidate the molecular mechanism involved in the fulminant mechanism of influenza. In addition, promote international exchange with researchers from the Tuberculosis Research Institute, Kitasato Research Institute, National Institute of Infectious Diseases, National Center for Global Health and Medical Sciences, and Institute of Medical Science, University of Tokyo, outside the Asia International Institute of Infectious Diseases Control, Teikyo University. doing. We are also promoting the Teikyo University ADC Lab Sakura Science Project (TASP) as an international exchange with Asian countries.

Teikyo University ADC Lab Sakura Science Project (TASP)

1. Invitation plan: Implementation of joint research on infectious disease control in collaboration with the Japan Science Promotion Organization Sakura Science Plan (SSP).

Positioned as joint research aimed at improving research and technology at participating facilities in Vietnam and the Philippines, the following three items of training will be provided.

  1. Biosafety
  2. Latest technology for virus / bacteria detection
  3. Public health and epidemiology

We aim to promote joint research by improving the research and technology of participating facilities from Vietnam, the Philippines and Laos. Research support: Senior Assistant Professor / technical guidance is top class at Asia International Institute of Infectious Diseases Control, Teikyo University, Tuberculosis Research Institute, Kitasato Research Institute, National Infectious Diseases Research Institute, National International Medical Research Center, and Institute of Medical Science, University of Tokyo. Researchers, doctors, and technical staff will support you.

We accepted 7 trainees from 3 countries, Vietnam, Philippines and Laos, and implemented the training program.

From November 16th to December 4th, 2015, the "Sakura Science Plan", which is a project adopted by JST (Japan Science and Technology Agency), was implemented, and ADC has seven trainees from three countries: Vietnam, the Philippines, and Laos. Was accepted. Seven people who are active in their own countries as researchers visited this training, and lectures on medical safety at the Safety Control Department of Teikyo University Hospital, Round, Central, with the themes of "infectious diseases" and "safety management". We deepened our interaction with our faculty members and students by visiting the inspection department and the pharmacy department, visiting our research facilities, experiencing practical training on the latest virus and bacteria detection techniques, and participating in classes. We also visited the Tuberculosis Research Institute (Kiyose City, Tokyo), which is in collaboration with the ADC Research Institute.

2. Dispatch plan: Dispatch of research and research on infectious disease control to Asian countries by Teikyo University students, Graduate School, and faculty members.

Inquiries

Asia International Institute of Infectious Diseases Control, Teikyo University

TEL
03-3964-8420(Direct)
TEL
03-3964-1211(Main)
E-mail
office-adc@med.teikyo-u.ac.jp