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A research group led by Professor Otowa identified, through whole-genome sequencing, the gene that determines the ameliorative effect of oxytocin nasal preparation on core characteristics of autism spectrum disorder. (Itabashi Campus

A research group led by Professor Kenji Otowa of the Department of Psychiatry and Neuroscience, Teikyo University School of Medicine, has identified the gene that determines the ameliorative effect of oxytocin nasal preparation on core characteristics of autism spectrum disorder through whole-genome analysis.
Based on these research findings, a possible strategy for optimizing treatment is to selectively administer oxytocin to patients who are likely to respond well to its treatment by identifying genetic polymorphisms in the type 2 ryanodine receptor before administration. Furthermore, it is expected that developing new therapeutic agents that target systems that regulate oxytocin secretion, such as the ryanodine receptor, will lead to the development of efficient and effective treatment methods.
The results of this research were published on March 28, 2026 (Saturday) in the medical journal "Molecular Psychiatry" published by the Nature Publishing Group.

The press release is available here.
Click here for more details about Professor Otowa.

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