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A research group led by Senior Assistant Professor Kamata Faculty of Pharmaceutical Sciences has elucidated the characteristic changes in blood components associated with "cancer-associated thrombosis," a condition that occurs in breast cancer.Itabashi Campus

Teikyo University Faculty of Pharmaceutical Sciences Laboratory of Bio-Defense Science Senior Assistant Professor Riyo Kamada, Laboratory Professor Naoki Ohkura, Laboratory of Drug Delivery Science Assistant Professor Risa Munakata, Laboratory Professor Ryo Suzuki, Theranostics Laboratory Researcher Ayori Kageyama, Faculty of Pharmaceutical Sciences Specially Appointed Professor Kazuo Maruyama and his research team have successfully identified in detail characteristic changes in blood components related to thrombosis (a condition where blood clots and obstructs blood vessels), an extremely important complication in cancer patients. Thrombosis is an extremely important complication in cancer patients.
Thrombosis associated with cancer is the second leading cause of death after cancer itself, and is an extremely important complication. The detailed mechanisms of how blood factors fluctuate and increase the risk of thrombosis, especially in breast cancer, which affects a large number of patients, have not been fully elucidated. The research team has succeeded in identifying in detail the changes in blood components associated with cancer progression through analysis using a mouse model of breast cancer. This achievement is expected to lead to advance prediction of the risk of cancer-related thrombosis, which is often fatal, by blood analysis, and to make a significant contribution to the establishment of risk assessment methods and the development of early treatment methods.
The research results were published in the December 2025 issue of the journal Biological and Pharmaceutical Bulletin. It was selected as a "Highlighted Paper selected by Editor-in-Chief" as a particularly outstanding study from among the papers in the issue, and was featured on the cover of the issue as a study that symbolizes outstanding content.

For more information on the academic journal, click here (English)
The published paper is available here (in English).

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